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1y4i

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[[Image:1y4i.png|left|200px]]
 
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{{STRUCTURE_1y4i| PDB=1y4i | SCENE= }}
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==Crystal structure of Citrobacter Freundii L-methionine-lyase==
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<StructureSection load='1y4i' size='340' side='right'caption='[[1y4i]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1y4i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y4I FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y4i OCA], [https://pdbe.org/1y4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y4i RCSB], [https://www.ebi.ac.uk/pdbsum/1y4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y4i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q84AR1_CITFR Q84AR1_CITFR]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y4/1y4i_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y4i ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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L-Methionine gamma-lyase (MGL) is a pyridoxal 5'-phosphate (PLP) dependent enzyme that catalyzes gamma-elimination of L-methionine. The crystal structure of MGL from Citrobacter freundii has been determined at 1.9 A resolution. The spatial fold of the protein is similar to those of MGLs from Pseudomonas putida and Trichomonas vaginalis. The comparison of these structures revealed that there are differences in PLP-binding residues and positioning of the surrounding flexible loops.
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===Crystal structure of Citrobacter Freundii L-methionine-lyase===
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Structure of Citrobacter freundii L-methionine gamma-lyase.,Mamaeva DV, Morozova EA, Nikulin AD, Revtovich SV, Nikonov SV, Garber MB, Demidkina TV Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jun 1;61(Pt, 6):546-9. Epub 2005 Jun 1. PMID:16511092<ref>PMID:16511092</ref>
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{{ABSTRACT_PUBMED_16511092}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1y4i" style="background-color:#fffaf0;"></div>
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==About this Structure==
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==See Also==
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[[1y4i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y4I OCA].
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*[[Methionine gamma-lyase 3D structures|Methionine gamma-lyase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:016511092</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Citrobacter freundii]]
[[Category: Citrobacter freundii]]
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[[Category: Methionine gamma-lyase]]
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[[Category: Large Structures]]
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[[Category: Demidkina, T V.]]
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[[Category: Demidkina TV]]
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[[Category: Garber, M B.]]
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[[Category: Garber MB]]
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[[Category: Mamaeva, D V.]]
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[[Category: Mamaeva DV]]
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[[Category: Morozova, E A.]]
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[[Category: Morozova EA]]
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[[Category: Nikonov, S V.]]
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[[Category: Nikonov SV]]
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[[Category: Nikulin, A D.]]
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[[Category: Nikulin AD]]
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[[Category: Revtovich, S V.]]
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[[Category: Revtovich SV]]
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[[Category: Lyase]]
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[[Category: Plp-dependent enzyme]]
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[[Category: Pyridoxal-5'-phosphate]]
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Current revision

Crystal structure of Citrobacter Freundii L-methionine-lyase

PDB ID 1y4i

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