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1y6j

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[[Image:1y6j.jpg|left|200px]]
 
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{{Structure
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==L-Lactate Dehydrogenase from Clostridium Thermocellum Cth-1135==
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|PDB= 1y6j |SIZE=350|CAPTION= <scene name='initialview01'>1y6j</scene>, resolution 3.01&Aring;
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<StructureSection load='1y6j' size='340' side='right'caption='[[1y6j]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1y6j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus Acetivibrio thermocellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y6J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y6J FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.01&#8491;</td></tr>
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|GENE= Cth-1135 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1515 Clostridium thermocellum])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y6j OCA], [https://pdbe.org/1y6j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y6j RCSB], [https://www.ebi.ac.uk/pdbsum/1y6j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y6j ProSAT], [https://www.topsan.org/Proteins/SECSG/1y6j TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK00066 ldh], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00300 LDH]</span>
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y6j OCA], [http://www.ebi.ac.uk/pdbsum/1y6j PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1y6j RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/A3DCA4_ACET2 A3DCA4_ACET2] Catalyzes the conversion of lactate to pyruvate.[HAMAP-Rule:MF_00488]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y6/1y6j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y6j ConSurf].
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<div style="clear:both"></div>
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'''L-Lactate Dehydrogenase from Clostridium Thermocellum Cth-1135'''
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==See Also==
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*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1Y6J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y6J OCA].
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[[Category: Acetivibrio thermocellus]]
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[[Category: Clostridium thermocellum]]
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[[Category: Large Structures]]
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[[Category: L-lactate dehydrogenase]]
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[[Category: Chen L]]
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[[Category: Single protein]]
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[[Category: Chen LR]]
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[[Category: Chen, L.]]
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[[Category: Habel J]]
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[[Category: Chen, L R.]]
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[[Category: Kataeva I]]
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[[Category: Habel, J.]]
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[[Category: Lee D]]
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[[Category: Kataeva, I.]]
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[[Category: Lin D]]
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[[Category: Lee, D.]]
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[[Category: Liu Z-J]]
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[[Category: Lin, D.]]
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[[Category: Ljungdahl L]]
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[[Category: Liu, Z J.]]
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[[Category: Rose J]]
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[[Category: Ljungdahl, L.]]
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[[Category: Tempel W]]
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[[Category: Rose, J.]]
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[[Category: Wang B-C]]
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[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
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[[Category: Yang H]]
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[[Category: Tempel, W.]]
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[[Category: Zhou W]]
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[[Category: Wang, B C.]]
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[[Category: Yang, H.]]
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[[Category: Zhou, W.]]
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[[Category: clostridium thermocellum]]
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[[Category: l-lactate dehydrogenase]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: secsg]]
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[[Category: southeast collaboratory for structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:13:46 2008''
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Current revision

L-Lactate Dehydrogenase from Clostridium Thermocellum Cth-1135

PDB ID 1y6j

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