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1zho

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==The structure of a ribosomal protein L1 in complex with mRNA==
==The structure of a ribosomal protein L1 in complex with mRNA==
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<StructureSection load='1zho' size='340' side='right' caption='[[1zho]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='1zho' size='340' side='right'caption='[[1zho]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zho]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZHO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZHO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zho]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZHO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZHO FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1i2a|1i2a]], [[1u63|1u63]], [[1dwu|1dwu]], [[1mzp|1mzp]], [[1ad2|1ad2]], [[1csj|1csj]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zho FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zho OCA], [https://pdbe.org/1zho PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zho RCSB], [https://www.ebi.ac.uk/pdbsum/1zho PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zho ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rplA, rpl1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zho FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zho OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zho RCSB], [http://www.ebi.ac.uk/pdbsum/1zho PDBsum]</span></td></tr>
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== Function ==
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<table>
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[https://www.uniprot.org/uniprot/RL1_THETH RL1_THETH] The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.[HAMAP-Rule:MF_01318] Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA (By similarity).[HAMAP-Rule:MF_01318]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zh/1zho_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zh/1zho_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zho ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1zho" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Garber, M.]]
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[[Category: Garber M]]
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[[Category: Kljashtorny, V.]]
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[[Category: Kljashtorny V]]
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[[Category: Kohrer, C.]]
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[[Category: Kohrer C]]
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[[Category: Nevskaya, N.]]
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[[Category: Nevskaya N]]
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[[Category: Nikonov, O.]]
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[[Category: Nikonov O]]
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[[Category: Nikonov, S.]]
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[[Category: Nikonov S]]
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[[Category: Nikonova, E.]]
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[[Category: Nikonova E]]
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[[Category: Nikulin, A.]]
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[[Category: Nikulin A]]
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[[Category: Piendl, W.]]
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[[Category: Piendl W]]
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[[Category: Stockley, P.]]
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[[Category: Stockley P]]
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[[Category: Tishchenko, S.]]
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[[Category: Tishchenko S]]
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[[Category: Volchkov, S.]]
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[[Category: Volchkov S]]
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[[Category: Zimmermann, R.]]
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[[Category: Zimmermann R]]
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[[Category: L1]]
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[[Category: Mrna-protein complex]]
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[[Category: Regulation of gene expression]]
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[[Category: Ribosomal protein]]
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[[Category: Ribosome]]
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[[Category: Rna-protein interaction]]
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[[Category: Structural protein-rna complex]]
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Current revision

The structure of a ribosomal protein L1 in complex with mRNA

PDB ID 1zho

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