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1zpe

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==Arginase I covalently modified with butylamine at Q19C==
==Arginase I covalently modified with butylamine at Q19C==
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<StructureSection load='1zpe' size='340' side='right' caption='[[1zpe]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='1zpe' size='340' side='right'caption='[[1zpe]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zpe]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zpe]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZPE FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BBC:3-[(4-AMINOBUTYL)SULFINYL]-2-IMINOPROPAN-1-OL'>BBC</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BBC:3-[(4-AMINOBUTYL)SULFINYL]-2-IMINOPROPAN-1-OL'>BBC</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tbj|1tbj]], [[1ta1|1ta1]], [[1tbh|1tbh]], [[1tbl|1tbl]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpe OCA], [https://pdbe.org/1zpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zpe RCSB], [https://www.ebi.ac.uk/pdbsum/1zpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zpe ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Arg1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
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</table>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>
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== Function ==
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zpe RCSB], [http://www.ebi.ac.uk/pdbsum/1zpe PDBsum]</span></td></tr>
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[https://www.uniprot.org/uniprot/ARGI1_RAT ARGI1_RAT]
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<table>
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== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zp/1zpe_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zp/1zpe_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zpe ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1zpe" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Arginase|Arginase]]
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*[[Arginase 3D structures|Arginase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arginase]]
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Ash, D E.]]
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[[Category: Ash DE]]
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[[Category: Cama, E.]]
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[[Category: Cama E]]
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[[Category: Christianson, D W.]]
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[[Category: Christianson DW]]
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[[Category: Colleluori, D M.]]
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[[Category: Colleluori DM]]
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[[Category: Compher, K.]]
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[[Category: Compher K]]
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[[Category: Cox, J D.]]
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[[Category: Cox JD]]
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[[Category: Emig, F A.]]
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[[Category: Emig FA]]
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[[Category: Han, S.]]
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[[Category: Han S]]
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[[Category: Jude, K.]]
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[[Category: Jude K]]
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[[Category: Reczkowski, R S.]]
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[[Category: Reczkowski RS]]
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[[Category: Scolnick, L R.]]
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[[Category: Scolnick LR]]
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[[Category: Viola, R E.]]
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[[Category: Viola RE]]
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[[Category: Chemically modified enzyme]]
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[[Category: Hydrolase]]
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Current revision

Arginase I covalently modified with butylamine at Q19C

PDB ID 1zpe

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