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1zx6

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[[Image:1zx6.jpg|left|200px]]
 
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{{Structure
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==High-resolution crystal structure of yeast Pin3 SH3 domain==
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|PDB= 1zx6 |SIZE=350|CAPTION= <scene name='initialview01'>1zx6</scene>, resolution 1.60&Aring;
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<StructureSection load='1zx6' size='340' side='right'caption='[[1zx6]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1zx6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZX6 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zx6 OCA], [https://pdbe.org/1zx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zx6 RCSB], [https://www.ebi.ac.uk/pdbsum/1zx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zx6 ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=[[1ynz|1YNZ]]
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zx6 OCA], [http://www.ebi.ac.uk/pdbsum/1zx6 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1zx6 RCSB]</span>
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[https://www.uniprot.org/uniprot/PIN3_YEAST PIN3_YEAST] Overproduction promotes the de novo induction of the [PSI+] prion form of SUP35. The prion-inducing effect depends on the association with the actin cytoskeleton. Also implicated in prion maintenance during heat stress.<ref>PMID:21777813</ref>
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''High-resolution crystal structure of yeast Pin3 SH3 domain'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/1zx6_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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1ZX6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZX6 OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zx6 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Kursula I]]
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[[Category: Kursula, I.]]
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[[Category: Kursula P]]
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[[Category: Kursula, P.]]
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[[Category: Lehmann F]]
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[[Category: Lehmann, F.]]
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[[Category: Song YH]]
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[[Category: Song, Y H.]]
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[[Category: Wilmanns M]]
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[[Category: Wilmanns, M.]]
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[[Category: Zou P]]
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[[Category: Zou, P.]]
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[[Category: sh3 domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:42:49 2008''
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Current revision

High-resolution crystal structure of yeast Pin3 SH3 domain

PDB ID 1zx6

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