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1zx6
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1zx6" size="450" color="white" frame="true" align="right" spinBox="true" caption="1zx6, resolution 1.60Å" /> '''High-resolution crys...) |
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| - | [[Image:1zx6.jpg|left|200px]]<br /><applet load="1zx6" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1zx6, resolution 1.60Å" /> | ||
| - | '''High-resolution crystal structure of yeast Pin3 SH3 domain'''<br /> | ||
| - | == | + | ==High-resolution crystal structure of yeast Pin3 SH3 domain== |
| - | + | <StructureSection load='1zx6' size='340' side='right'caption='[[1zx6]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1zx6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZX6 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zx6 OCA], [https://pdbe.org/1zx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zx6 RCSB], [https://www.ebi.ac.uk/pdbsum/1zx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zx6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PIN3_YEAST PIN3_YEAST] Overproduction promotes the de novo induction of the [PSI+] prion form of SUP35. The prion-inducing effect depends on the association with the actin cytoskeleton. Also implicated in prion maintenance during heat stress.<ref>PMID:21777813</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/1zx6_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zx6 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | + | [[Category: Kursula I]] | |
| - | [[Category: Kursula | + | [[Category: Kursula P]] |
| - | [[Category: Kursula | + | [[Category: Lehmann F]] |
| - | [[Category: Lehmann | + | [[Category: Song YH]] |
| - | [[Category: Song | + | [[Category: Wilmanns M]] |
| - | [[Category: Wilmanns | + | [[Category: Zou P]] |
| - | [[Category: Zou | + | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
High-resolution crystal structure of yeast Pin3 SH3 domain
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