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1zyk

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Current revision (07:16, 23 August 2023) (edit) (undo)
 
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<StructureSection load='1zyk' size='340' side='right'caption='[[1zyk]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='1zyk' size='340' side='right'caption='[[1zyk]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zyk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZYK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zyk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZYK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BE2:2-AMINOBENZOIC+ACID'>BE2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1o17|1o17]], [[1gxb|1gxb]], [[1xfm|1xfm]], [[1zxy|1zxy]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BE2:2-AMINOBENZOIC+ACID'>BE2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zyk OCA], [https://pdbe.org/1zyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zyk RCSB], [https://www.ebi.ac.uk/pdbsum/1zyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zyk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zyk OCA], [https://pdbe.org/1zyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zyk RCSB], [https://www.ebi.ac.uk/pdbsum/1zyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zyk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TRPD_SULSO TRPD_SULSO]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<ref>PMID:11298741</ref> <ref>PMID:16714288</ref>
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[https://www.uniprot.org/uniprot/TRPD_SACS2 TRPD_SACS2] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).[HAMAP-Rule:MF_00211]<ref>PMID:11298741</ref> <ref>PMID:16714288</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anthranilate phosphoribosyltransferase]]
 
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[[Category: Atcc 35091]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Deuss, M]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Marino, M]]
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[[Category: Deuss M]]
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[[Category: Mayans, O]]
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[[Category: Marino M]]
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[[Category: Sterner, R]]
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[[Category: Mayans O]]
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[[Category: Anthranilate]]
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[[Category: Sterner R]]
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[[Category: Prpp]]
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[[Category: Transferase]]
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[[Category: Trpd]]
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Current revision

Anthranilate Phosphoribosyltransferase in complex with PRPP, anthranilate and magnesium

PDB ID 1zyk

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