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1zzb
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==Crystal Structure of CoII HppE in Complex with Substrate== | ==Crystal Structure of CoII HppE in Complex with Substrate== | ||
| - | <StructureSection load='1zzb' size='340' side='right' caption='[[1zzb]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='1zzb' size='340' side='right'caption='[[1zzb]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1zzb]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1zzb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_wedmorensis Streptomyces wedmorensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZZB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZZB FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=S0H:(S)-2-HYDROXYPROPYLPHOSPHONIC+ACID'>S0H</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zzb OCA], [https://pdbe.org/1zzb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zzb RCSB], [https://www.ebi.ac.uk/pdbsum/1zzb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zzb ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HPPE_STRWE HPPE_STRWE] Non-heme-dependent dioxygenase that catalyzes the oxidative epoxidation of (S)-2-hydroxypropylphosphonate into (1R,2S)-epoxypropylphosphonate, the final step in the biosynthesis of fosfomycin antibiotic.<ref>PMID:16015285</ref> <ref>PMID:16186494</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</div> | </div> | ||
<div class="pdbe-citations 1zzb" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1zzb" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Epoxidase 3D structures|Epoxidase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Drennan | + | [[Category: Streptomyces wedmorensis]] |
| - | [[Category: Higgins | + | [[Category: Drennan CL]] |
| - | [[Category: Liu | + | [[Category: Higgins LJ]] |
| - | [[Category: Liu | + | [[Category: Liu HW]] |
| - | [[Category: Yan | + | [[Category: Liu P]] |
| - | + | [[Category: Yan F]] | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of CoII HppE in Complex with Substrate
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