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2adi

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==Crystal structure of monoclonal anti-CD4 antibody Q425 in complex with Barium==
==Crystal structure of monoclonal anti-CD4 antibody Q425 in complex with Barium==
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<StructureSection load='2adi' size='340' side='right' caption='[[2adi]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='2adi' size='340' side='right'caption='[[2adi]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2adi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ADI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ADI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2adi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ADI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ADI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2adg|2adg]], [[2adj|2adj]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2adi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2adi OCA], [http://pdbe.org/2adi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2adi RCSB], [http://www.ebi.ac.uk/pdbsum/2adi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2adi ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2adi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2adi OCA], [https://pdbe.org/2adi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2adi RCSB], [https://www.ebi.ac.uk/pdbsum/2adi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2adi ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ad/2adi_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ad/2adi_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[3D structures of monoclonal antibody|3D structures of monoclonal antibody]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Hamer, D H]]
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[[Category: Mus musculus]]
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[[Category: Hendrickson, W A]]
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[[Category: Hamer DH]]
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[[Category: Kwong, P D]]
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[[Category: Hendrickson WA]]
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[[Category: Sattentau, Q J]]
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[[Category: Kwong PD]]
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[[Category: Zhou, T]]
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[[Category: Sattentau QJ]]
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[[Category: Anti-cd4]]
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[[Category: Zhou T]]
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[[Category: Antibody recognition]]
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[[Category: Immune system]]
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[[Category: Interfacial metal]]
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Current revision

Crystal structure of monoclonal anti-CD4 antibody Q425 in complex with Barium

PDB ID 2adi

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