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2b05
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2b05" size="450" color="white" frame="true" align="right" spinBox="true" caption="2b05, resolution 2.55Å" /> '''Crystal Structure o...) |
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| - | [[Image:2b05.gif|left|200px]]<br /> | ||
| - | <applet load="2b05" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2b05, resolution 2.55Å" /> | ||
| - | '''Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide'''<br /> | ||
| - | == | + | ==Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide== |
| - | + | <StructureSection load='2b05' size='340' side='right'caption='[[2b05]], [[Resolution|resolution]] 2.55Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[2b05]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B05 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55Å</td></tr> |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b05 OCA], [https://pdbe.org/2b05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b05 RCSB], [https://www.ebi.ac.uk/pdbsum/2b05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b05 ProSAT]</span></td></tr> |
| - | [ | + | </table> |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/1433G_HUMAN 1433G_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.<ref>PMID:16511572</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[ | + | Check<jmol> |
| - | [ | + | <jmolCheckbox> |
| - | [[ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b0/2b05_consurf.spt"</scriptWhenChecked> |
| - | [ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b05 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[14-3-3 protein 3D structures|14-3-3 protein 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith C]] | ||
| + | [[Category: Debreczeni EJ]] | ||
| + | [[Category: Doyle D]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Elkins J]] | ||
| + | [[Category: Papagrigoriou E]] | ||
| + | [[Category: Turnbull A]] | ||
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Yang X]] | ||
| + | [[Category: Zhao Y]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Debreczeni EJ | Doyle D | Edwards A | Elkins J | Papagrigoriou E | Turnbull A | Weigelt J | Yang X | Zhao Y | Von Delft F
