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2bbw

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==Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate==
==Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate==
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<StructureSection load='2bbw' size='340' side='right' caption='[[2bbw]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='2bbw' size='340' side='right'caption='[[2bbw]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2bbw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BBW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2bbw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BBW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GP5:DIGUANOSINE-PENTAPHOSPHATE'>GP5</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ar7|2ar7]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GP5:DIGUANOSINE-PENTAPHOSPHATE'>GP5</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AK4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbw OCA], [https://pdbe.org/2bbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bbw RCSB], [https://www.ebi.ac.uk/pdbsum/2bbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbw ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenylate_kinase Adenylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.3 2.7.4.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbw OCA], [http://pdbe.org/2bbw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bbw RCSB], [http://www.ebi.ac.uk/pdbsum/2bbw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbw ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/KAD4_HUMAN KAD4_HUMAN]] Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. May also be active with GTP (By similarity).
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[https://www.uniprot.org/uniprot/KAD4_HUMAN KAD4_HUMAN] Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. May also be active with GTP (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Adenylate kinase|Adenylate kinase]]
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*[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Adenylate kinase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C]]
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[[Category: Arrowsmith C]]
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[[Category: Bunkoczi, G]]
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[[Category: Bunkoczi G]]
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[[Category: Debreczeni, J]]
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[[Category: Debreczeni J]]
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[[Category: Delft, F von]]
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[[Category: Edwards A]]
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[[Category: Edwards, A]]
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[[Category: Fedorov O]]
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[[Category: Fedorov, O]]
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[[Category: Filippakopoulos P]]
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[[Category: Filippakopoulos, P]]
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[[Category: Knapp S]]
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[[Category: Knapp, S]]
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[[Category: Niesen F]]
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[[Category: Niesen, F]]
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[[Category: Sundstrom M]]
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[[Category: Structural genomic]]
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[[Category: Turnbull AP]]
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[[Category: Sundstrom, M]]
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[[Category: Ugochukwu E]]
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[[Category: Turnbull, A P]]
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[[Category: Weigelt J]]
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[[Category: Ugochukwu, E]]
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[[Category: Von Delft F]]
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[[Category: Weigelt, J]]
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[[Category: Ak4]]
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[[Category: Nucleotide binding]]
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[[Category: Nucleotide kinase]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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Current revision

Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate

PDB ID 2bbw

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