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2f6i

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==Crystal structure of the ClpP protease catalytic domain from Plasmodium falciparum==
==Crystal structure of the ClpP protease catalytic domain from Plasmodium falciparum==
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<StructureSection load='2f6i' size='340' side='right' caption='[[2f6i]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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<StructureSection load='2f6i' size='340' side='right'caption='[[2f6i]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2f6i]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F6I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F6I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2f6i]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F6I FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f6i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f6i RCSB], [http://www.ebi.ac.uk/pdbsum/2f6i PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f6i OCA], [https://pdbe.org/2f6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f6i RCSB], [https://www.ebi.ac.uk/pdbsum/2f6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f6i ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O97252_PLAF7 O97252_PLAF7]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/2f6i_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/2f6i_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f6i ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2f6i" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Clp protease 3D structures|Clp protease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Endopeptidase Clp]]
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[[Category: Large Structures]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
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[[Category: Amani, M.]]
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[[Category: Amani M]]
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[[Category: Arrowsmith, C.]]
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[[Category: Arrowsmith C]]
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[[Category: Bray, J.]]
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[[Category: Bray J]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Finerty, P.]]
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[[Category: Finerty P]]
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[[Category: Hui, R.]]
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[[Category: Hui R]]
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[[Category: Loppnau, P.]]
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[[Category: Loppnau P]]
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[[Category: Mulichak, A.]]
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[[Category: Mulichak A]]
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[[Category: Plotnikova, O.]]
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[[Category: Plotnikova O]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Sundstrom M]]
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[[Category: Sundstrom, M.]]
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[[Category: Vedadi M]]
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[[Category: Vedadi, M.]]
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[[Category: Wasney G]]
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[[Category: Wasney, G.]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J.]]
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[[Category: Clp protease]]
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[[Category: Hydrolase]]
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[[Category: Sgc]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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Current revision

Crystal structure of the ClpP protease catalytic domain from Plasmodium falciparum

PDB ID 2f6i

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