This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2xnt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:01, 23 August 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
==ACETYLCHOLINE BINDING PROTEIN (ACHBP) AS TEMPLATE FOR HIERARCHICAL IN SILICO SCREENING PROCEDURES TO IDENTIFY STRUCTURALLY NOVEL LIGANDS FOR THE NICOTINIC RECEPTORS==
+
 
-
<StructureSection load='2xnt' size='340' side='right' caption='[[2xnt]], [[Resolution|resolution]] 3.21&Aring;' scene=''>
+
==Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors==
 +
<StructureSection load='2xnt' size='340' side='right'caption='[[2xnt]], [[Resolution|resolution]] 3.21&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2xnt]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XNT FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2xnt]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XNT FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=VU2:(2S)-2-[(4-CHLOROBENZYL)OXY]-2-PHENYLETHANAMINE'>VU2</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.21&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wn9|2wn9]], [[2w8f|2w8f]], [[2byp|2byp]], [[2c9t|2c9t]], [[2byq|2byq]], [[2w8g|2w8g]], [[2x00|2x00]], [[2uz6|2uz6]], [[2wnl|2wnl]], [[2br7|2br7]], [[2br8|2br8]], [[2byr|2byr]], [[2byn|2byn]], [[2bys|2bys]], [[2wnj|2wnj]], [[2w8e|2w8e]], [[2wzy|2wzy]], [[2wnc|2wnc]], [[2xnv|2xnv]], [[2xnu|2xnu]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=VU2:(2S)-2-[(4-CHLOROBENZYL)OXY]-2-PHENYLETHANAMINE'>VU2</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xnt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xnt RCSB], [http://www.ebi.ac.uk/pdbsum/2xnt PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xnt OCA], [https://pdbe.org/2xnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xnt RCSB], [https://www.ebi.ac.uk/pdbsum/2xnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xnt ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q8WSF8_APLCA Q8WSF8_APLCA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 15: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2xnt" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Acetylcholine binding protein|Acetylcholine binding protein]]
+
*[[Acetylcholine binding protein 3D structures|Acetylcholine binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 23: Line 27:
</StructureSection>
</StructureSection>
[[Category: Aplysia californica]]
[[Category: Aplysia californica]]
-
[[Category: Akdemir, A]]
+
[[Category: Large Structures]]
-
[[Category: Deesch, I]]
+
[[Category: Akdemir A]]
-
[[Category: Rucktooa, P]]
+
[[Category: Rucktooa P]]
-
[[Category: Sixma, T K]]
+
[[Category: Sixma TK]]
-
[[Category: Choline-binding protein]]
+
[[Category: DeEsch I]]
-
[[Category: Cys-loop receptor]]
+
-
[[Category: Electrophysiology]]
+
-
[[Category: In-silico screening]]
+
-
[[Category: Ligand-gated ion channel]]
+
-
[[Category: Receptor]]
+

Current revision

Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors

PDB ID 2xnt

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2xnt"
Personal tools