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2f8a
From Proteopedia
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| - | [[Image:2f8a.gif|left|200px]]<br /><applet load="2f8a" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2f8a, resolution 1.50Å" /> | ||
| - | '''Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1'''<br /> | ||
| - | == | + | ==Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1== |
| - | + | <StructureSection load='2f8a' size='340' side='right'caption='[[2f8a]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2f8a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F8A FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f8a OCA], [https://pdbe.org/2f8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f8a RCSB], [https://www.ebi.ac.uk/pdbsum/2f8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f8a ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GPX1_HUMAN GPX1_HUMAN] Protects the hemoglobin in erythrocytes from oxidative breakdown. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f8/2f8a_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f8a ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Glutathione peroxidase|Glutathione peroxidase]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | + | [[Category: Edwards A]] | |
| - | [[Category: Edwards | + | [[Category: Gileadi O]] |
| - | [[Category: Gileadi | + | [[Category: Johansson C]] |
| - | [[Category: Johansson | + | [[Category: Kavanagh KL]] |
| - | [[Category: Kavanagh | + | [[Category: Oppermann U]] |
| - | [[Category: Oppermann | + | [[Category: Smee C]] |
| - | + | [[Category: Sundstrom M]] | |
| - | [[Category: Smee | + | [[Category: Weigelt J]] |
| - | [[Category: Sundstrom | + | [[Category: Von Delft F]] |
| - | [[Category: Weigelt | + | |
| - | [[Category: | + | |
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Current revision
Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1
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Categories: Homo sapiens | Large Structures | Edwards A | Gileadi O | Johansson C | Kavanagh KL | Oppermann U | Smee C | Sundstrom M | Weigelt J | Von Delft F
