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2fyi

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==Crystal Structure of the Cofactor-Binding Domain of the Cbl Transcriptional Regulator==
==Crystal Structure of the Cofactor-Binding Domain of the Cbl Transcriptional Regulator==
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<StructureSection load='2fyi' size='340' side='right' caption='[[2fyi]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='2fyi' size='340' side='right'caption='[[2fyi]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2fyi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FYI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2fyi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FYI FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cbl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fyi OCA], [http://pdbe.org/2fyi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fyi RCSB], [http://www.ebi.ac.uk/pdbsum/2fyi PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fyi OCA], [https://pdbe.org/2fyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fyi RCSB], [https://www.ebi.ac.uk/pdbsum/2fyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fyi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CBL_ECOLI CBL_ECOLI]] May be an accessory regulatory protein within the cys regulon.
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[https://www.uniprot.org/uniprot/CBL_ECOLI CBL_ECOLI] May be an accessory regulatory protein within the cys regulon.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fy/2fyi_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fy/2fyi_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fyi ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Brzozowski, A M]]
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[[Category: Large Structures]]
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[[Category: Bujacz, G D]]
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[[Category: Brzozowski AM]]
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[[Category: Neumann, P]]
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[[Category: Bujacz GD]]
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[[Category: Stec, E]]
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[[Category: Neumann P]]
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[[Category: Wilkinson, A J]]
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[[Category: Stec E]]
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[[Category: Cofactor-binding domain]]
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[[Category: Wilkinson AJ]]
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[[Category: Cysteine biosynthesis]]
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[[Category: Lys-r family]]
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[[Category: Transcription]]
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[[Category: Transcriptional regulator]]
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Current revision

Crystal Structure of the Cofactor-Binding Domain of the Cbl Transcriptional Regulator

PDB ID 2fyi

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