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2gf3

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[[Image:2gf3.png|left|200px]]
 
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{{STRUCTURE_2gf3| PDB=2gf3 | SCENE= }}
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==Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution.==
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<StructureSection load='2gf3' size='340' side='right'caption='[[2gf3]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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===Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2gf3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._(in:_Bacteria) Bacillus sp. (in: Bacteria)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GF3 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10368302}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FOA:2-FUROIC+ACID'>FOA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf3 OCA], [https://pdbe.org/2gf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gf3 RCSB], [https://www.ebi.ac.uk/pdbsum/2gf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf3 ProSAT]</span></td></tr>
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[[2gf3]] is a 2 chain structure of [[Sarcosine oxidase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp. Bacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF3 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MSOX_BACB0 MSOX_BACB0] Catalyzes the oxidative demethylation of sarcosine. Can also oxidize other secondary amino acids such as N-methyl-L-alanine.[HAMAP-Rule:MF_00516]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gf3 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Sarcosine oxidase|Sarcosine oxidase]]
*[[Sarcosine oxidase|Sarcosine oxidase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010368302</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Bacillus sp.]]
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[[Category: Chen Z]]
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[[Category: Sarcosine oxidase]]
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[[Category: Jorns MS]]
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[[Category: Chen, Z.]]
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[[Category: Mathews FS]]
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[[Category: Jorns, M S.]]
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[[Category: Trickey P]]
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[[Category: Mathews, F S.]]
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[[Category: Trickey, P.]]
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[[Category: Flavoprotein oxidase]]
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[[Category: Inhibitor 2-furoic acid]]
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[[Category: Oxidoreductase]]
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Current revision

Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution.

PDB ID 2gf3

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