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2gps

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==Crystal Structure of the Biotin Carboxylase Subunit, E23R mutant, of Acetyl-CoA Carboxylase from Escherichia coli.==
==Crystal Structure of the Biotin Carboxylase Subunit, E23R mutant, of Acetyl-CoA Carboxylase from Escherichia coli.==
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<StructureSection load='2gps' size='340' side='right' caption='[[2gps]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='2gps' size='340' side='right'caption='[[2gps]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2gps]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GPS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GPS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2gps]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GPS FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w93|1w93]], [[1w96|1w96]], [[1dv1|1dv1]], [[1dv2|1dv2]], [[1bnc|1bnc]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">accC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gps OCA], [https://pdbe.org/2gps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gps RCSB], [https://www.ebi.ac.uk/pdbsum/2gps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gps ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Biotin_carboxylase Biotin carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.14 6.3.4.14] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gps OCA], [http://pdbe.org/2gps PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gps RCSB], [http://www.ebi.ac.uk/pdbsum/2gps PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gps ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ACCC_ECOLI ACCC_ECOLI]] This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
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[https://www.uniprot.org/uniprot/ACCC_ECOLI ACCC_ECOLI] This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Acetyl-CoA carboxylase|Acetyl-CoA carboxylase]]
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*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Biotin carboxylase]]
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[[Category: Large Structures]]
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[[Category: Chang, G G]]
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[[Category: Chang GG]]
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[[Category: Chou, C Y]]
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[[Category: Chou CY]]
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[[Category: Shen, Y]]
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[[Category: Shen Y]]
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[[Category: Tong, L]]
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[[Category: Tong L]]
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[[Category: Atp-grasp]]
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[[Category: Biotin-dependent]]
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[[Category: Carboxylase]]
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[[Category: Dimer-interface mutant]]
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[[Category: Fatty acid synthesis]]
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[[Category: Ligase]]
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Current revision

Crystal Structure of the Biotin Carboxylase Subunit, E23R mutant, of Acetyl-CoA Carboxylase from Escherichia coli.

PDB ID 2gps

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