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2gsh
From Proteopedia
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==Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium== | ==Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium== | ||
| - | <StructureSection load='2gsh' size='340' side='right' caption='[[2gsh]], [[Resolution|resolution]] 2.39Å' scene=''> | + | <StructureSection load='2gsh' size='340' side='right'caption='[[2gsh]], [[Resolution|resolution]] 2.39Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2gsh]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2gsh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GSH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GSH FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.393Å</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gsh OCA], [https://pdbe.org/2gsh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gsh RCSB], [https://www.ebi.ac.uk/pdbsum/2gsh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gsh ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2gsh TOPSAN]</span></td></tr> | |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </table> |
| - | <table> | + | == Function == |
| + | [https://www.uniprot.org/uniprot/RHMD_SALTY RHMD_SALTY] Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR). Can also dehydrate L-lyxonate and L-mannonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate.<ref>PMID:18754693</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/2gsh_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/2gsh_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gsh ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Salmonella enterica subsp. enterica serovar | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]] |
| - | [[Category: Adams | + | [[Category: Adams JM]] |
| - | [[Category: Almo | + | [[Category: Almo SC]] |
| - | [[Category: Burley | + | [[Category: Burley SK]] |
| - | [[Category: Dickey | + | [[Category: Dickey M]] |
| - | [[Category: Gerlt | + | [[Category: Gerlt J]] |
| - | [[Category: Malashkevich | + | [[Category: Malashkevich VN]] |
| - | + | [[Category: Patskovsky Y]] | |
| - | [[Category: Patskovsky | + | [[Category: Sauder JM]] |
| - | [[Category: Sauder | + | [[Category: Wasserman SR]] |
| - | [[Category: Wasserman | + | |
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Current revision
Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium
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