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2gw8

From Proteopedia

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Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 resolution

Structural highlights

2gw8 is a 1 chain structure with sequence from Neisseria meningitidis MC58. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.85Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q9JXK6_NEIMB

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The P(II) signal transduction proteins GlnB and GlnK are implicated in the regulation of nitrogen assimilation in Escherichia coli and other enteric bacteria. P(II)-like proteins are widely distributed in bacteria, archaea and plants. In contrast to other bacteria, Neisseria are limited to a single P(II) protein (NMB 1995), which shows a high level of sequence identity to GlnB and GlnK from Escherichia coli (73 and 62%, respectively). The structure of the P(II) protein from N. meningitidis (serotype B) has been solved by molecular replacement to a resolution of 1.85 A. Comparison of the structure with those of other P(II) proteins shows that the overall fold is tightly conserved across the whole population of related proteins, in particular the positions of the residues implicated in ATP binding. It is proposed that the Neisseria P(II) protein shares functions with GlnB/GlnK of enteric bacteria.

Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 A resolution.,Nichols CE, Sainsbury S, Berrow NS, Alderton D, Saunders NJ, Stammers DK, Owens RJ Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt, 6):494-7. Epub 2006 May 31. PMID:16754965^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Nichols CE, Sainsbury S, Berrow NS, Alderton D, Saunders NJ, Stammers DK, Owens RJ. Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 A resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 1;62(Pt, 6):494-7. Epub 2006 May 31. PMID:16754965 doi:http://dx.doi.org/10.1107/S1744309106015430

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2gw8"

@@ Line 3: / Line 3: @@
 <StructureSection load='2gw8' size='340' side='right'caption='[[2gw8]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2gw8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neimb Neimb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GW8 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2gw8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_MC58 Neisseria meningitidis MC58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GW8 FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NMB1955 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=122586 NEIMB])</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gw8 OCA], [https://pdbe.org/2gw8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gw8 RCSB], [https://www.ebi.ac.uk/pdbsum/2gw8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gw8 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q9JXK6_NEIMB Q9JXK6_NEIMB]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 31: / Line 33: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Neimb]]
+[[Category: Neisseria meningitidis MC58]]
-[[Category: Alderton, D]]
+[[Category: Alderton D]]
-[[Category: Berrow, N S]]
+[[Category: Berrow NS]]
-[[Category: Nichols, C E]]
+[[Category: Nichols CE]]
-[[Category: OPPF, Oxford Protein Production Facility]]
+[[Category: Owens RJ]]
-[[Category: Owens, R J]]
+[[Category: Sainsbury S]]
-[[Category: Sainsbury, S]]
+[[Category: Stammers DK]]
-[[Category: Stammers, D K]]
-[[Category: Neisseria]]
-[[Category: Oppf]]
-[[Category: Oxford protein production facility]]
-[[Category: Pii]]
-[[Category: Signal transduction]]
-[[Category: Signaling protein]]
-[[Category: Structural genomic]]
-[[Category: Transcriptional regulation]]

2gw8

From Proteopedia

Current revision

Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 resolution

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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