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2h84

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==Crystal Structure of the C-terminal Type III Polyketide Synthase (PKS III) Domain of 'Steely1' (a Type I/III PKS Hybrid from Dictyostelium)==
==Crystal Structure of the C-terminal Type III Polyketide Synthase (PKS III) Domain of 'Steely1' (a Type I/III PKS Hybrid from Dictyostelium)==
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<StructureSection load='2h84' size='340' side='right' caption='[[2h84]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<StructureSection load='2h84' size='340' side='right'caption='[[2h84]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2h84]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum_ax4 Dictyostelium discoideum ax4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H84 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H84 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2h84]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum_AX4 Dictyostelium discoideum AX4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H84 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h84 OCA], [http://pdbe.org/2h84 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2h84 RCSB], [http://www.ebi.ac.uk/pdbsum/2h84 PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h84 OCA], [https://pdbe.org/2h84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h84 RCSB], [https://www.ebi.ac.uk/pdbsum/2h84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h84 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PKS1_DICDI PKS1_DICDI]] Probable polyketide synthase (By similarity). Produces only acylpyrones; in vitro.<ref>PMID:16906151</ref>
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[https://www.uniprot.org/uniprot/PKS1_DICDI PKS1_DICDI] Probable polyketide synthase (By similarity). Produces only acylpyrones; in vitro.<ref>PMID:16906151</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/2h84_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/2h84_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Dictyostelium discoideum ax4]]
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[[Category: Dictyostelium discoideum AX4]]
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[[Category: Austin, M B]]
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[[Category: Large Structures]]
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[[Category: Bowman, M E]]
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[[Category: Austin MB]]
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[[Category: Haydock, S]]
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[[Category: Bowman ME]]
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[[Category: Kato, A]]
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[[Category: Haydock S]]
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[[Category: Kay, R R]]
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[[Category: Kato A]]
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[[Category: Moore, B S]]
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[[Category: Kay RR]]
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[[Category: Noel, J P]]
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[[Category: Moore BS]]
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[[Category: Saito, T]]
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[[Category: Noel JP]]
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[[Category: Biosynthetic protein]]
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[[Category: Saito T]]
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[[Category: Chalcone-stilbene synthase superfamily]]
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[[Category: Fa]]
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[[Category: Pk]]
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[[Category: Thiolase-fold]]
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[[Category: Transferase]]
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[[Category: Type i fatty acid synthase]]
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[[Category: Type i pk]]
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[[Category: Type iii polyketide synthase]]
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Current revision

Crystal Structure of the C-terminal Type III Polyketide Synthase (PKS III) Domain of 'Steely1' (a Type I/III PKS Hybrid from Dictyostelium)

PDB ID 2h84

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