This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2hf2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:57, 30 August 2023) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2hf2.gif|left|200px]]
 
-
<!--
+
==Domain shifting confirms monomeric structure of Escherichia sugar phosphatase SUPH==
-
The line below this paragraph, containing "STRUCTURE_2hf2", creates the "Structure Box" on the page.
+
<StructureSection load='2hf2' size='340' side='right'caption='[[2hf2]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2hf2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HF2 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
{{STRUCTURE_2hf2| PDB=2hf2 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hf2 OCA], [https://pdbe.org/2hf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hf2 RCSB], [https://www.ebi.ac.uk/pdbsum/2hf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hf2 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2hf2 TOPSAN]</span></td></tr>
-
 
+
</table>
-
'''Domain shifting confirms monomeric structure of Escherichia sugar phosphatase SUPH'''
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/SUPH_ECOLI SUPH_ECOLI] Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of ribose-5-phosphate, glucose-6-phosphate, fructose-1-phosphate, acetyl-phosphate, glycerol-1-phosphate, glycerol-2-phosphate, 2-deoxy-glucose-6-phosphate, mannose-6-phosphate and fructose-6-phosphate. Appears to have a low level of phosphotransferase activity using monophosphates as the phosphate donor.<ref>PMID:15808744</ref> <ref>PMID:16990279</ref> <ref>PMID:15657928</ref>
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
2HF2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HF2 OCA].
+
Check<jmol>
-
[[Category: Escherichia coli]]
+
<jmolCheckbox>
-
[[Category: Single protein]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hf/2hf2_consurf.spt"</scriptWhenChecked>
-
[[Category: Sugar-phosphatase]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Almo, S C.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Burley, S K.]]
+
</jmolCheckbox>
-
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hf2 ConSurf].
-
[[Category: Patskovsky, Y.]]
+
<div style="clear:both"></div>
-
[[Category: Ramagopal, U.]]
+
== References ==
-
[[Category: Had family]]
+
<references/>
-
[[Category: New york structural genomix research consortium]]
+
__TOC__
-
[[Category: Nysgxrc]]
+
</StructureSection>
-
[[Category: Phosphatase]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Protein structure initiative]]
+
[[Category: Large Structures]]
-
[[Category: Psi]]
+
[[Category: Almo SC]]
-
[[Category: Structural genomic]]
+
[[Category: Burley SK]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:12:57 2008''
+
[[Category: Patskovsky Y]]
 +
[[Category: Ramagopal U]]

Current revision

Domain shifting confirms monomeric structure of Escherichia sugar phosphatase SUPH

PDB ID 2hf2

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2hf2"
Personal tools