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2nq5

From Proteopedia

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[[Image:2nq5.gif|left|200px]]
 
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{{Structure
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==Crystal structure of methyltransferase from Streptococcus mutans==
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|PDB= 2nq5 |SIZE=350|CAPTION= <scene name='initialview01'>2nq5</scene>, resolution 1.90&Aring;
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<StructureSection load='2nq5' size='340' side='right'caption='[[2nq5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2nq5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NQ5 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE= metE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nq5 OCA], [https://pdbe.org/2nq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nq5 RCSB], [https://www.ebi.ac.uk/pdbsum/2nq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nq5 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2nq5 TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK05222 PRK05222], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03311 CIMS_C_terminal_like], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03312 CIMS_N_terminal_like]</span>
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nq5 OCA], [http://www.ebi.ac.uk/pdbsum/2nq5 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2nq5 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/METE_STRMU METE_STRMU] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nq/2nq5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nq5 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of methyltransferase from Streptococcus mutans'''
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==See Also==
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*[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2NQ5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NQ5 OCA].
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[[Category: Large Structures]]
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[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
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[[Category: Single protein]]
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[[Category: Streptococcus mutans]]
[[Category: Streptococcus mutans]]
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[[Category: Almo, S C.]]
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[[Category: Almo SC]]
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[[Category: Burley, S K.]]
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[[Category: Burley SK]]
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[[Category: Fedorov, A A.]]
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[[Category: Fedorov AA]]
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[[Category: Fedorov, E V.]]
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[[Category: Fedorov EV]]
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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[[Category: Sauder JM]]
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[[Category: Sauder, J M.]]
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[[Category: methyltransferase]]
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[[Category: new york structural genomix research consortium]]
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[[Category: nysgxrc]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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[[Category: target 6426d]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:34:33 2008''
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Current revision

Crystal structure of methyltransferase from Streptococcus mutans

PDB ID 2nq5

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