2nwc

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Current revision (10:23, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2nwc' size='340' side='right'caption='[[2nwc]], [[Resolution|resolution]] 3.02&Aring;' scene=''>
<StructureSection load='2nwc' size='340' side='right'caption='[[2nwc]], [[Resolution|resolution]] 3.02&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2nwc]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NWC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2nwc]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NWC FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">groL, groEL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.02&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chaperonin_ATPase Chaperonin ATPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.9 3.6.4.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nwc OCA], [https://pdbe.org/2nwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nwc RCSB], [https://www.ebi.ac.uk/pdbsum/2nwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nwc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nwc OCA], [https://pdbe.org/2nwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nwc RCSB], [https://www.ebi.ac.uk/pdbsum/2nwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nwc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CH60_ECOUT CH60_ECOUT]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).
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[https://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Chaperonin 3D structures|Chaperonin 3D structures]]
 
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Chaperonin ATPase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kiser, P D]]
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[[Category: Kiser PD]]
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[[Category: Lodowski, D T]]
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[[Category: Lodowski DT]]
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[[Category: Palczewski, K]]
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[[Category: Palczewski K]]
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[[Category: Chaperone]]
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[[Category: Chaperonin]]
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[[Category: Hsp60]]
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Current revision

A 3.02 angstrom crystal structure of wild-type apo GroEL in a monoclinic space group

PDB ID 2nwc

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