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2oy4

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==Uninhibited human MMP-8==
==Uninhibited human MMP-8==
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<StructureSection load='2oy4' size='340' side='right' caption='[[2oy4]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='2oy4' size='340' side='right'caption='[[2oy4]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2oy4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OY4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2oy4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OY4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bzs|1bzs]], [[2oy2|2oy2]], [[2oxu|2oxu]], [[2oxw|2oxw]], [[2oxz|2oxz]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MMP8, CLG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oy4 OCA], [https://pdbe.org/2oy4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oy4 RCSB], [https://www.ebi.ac.uk/pdbsum/2oy4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oy4 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Neutrophil_collagenase Neutrophil collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.34 3.4.24.34] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oy4 OCA], [http://pdbe.org/2oy4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2oy4 RCSB], [http://www.ebi.ac.uk/pdbsum/2oy4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2oy4 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MMP8_HUMAN MMP8_HUMAN]] Can degrade fibrillar type I, II, and III collagens.
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[https://www.uniprot.org/uniprot/MMP8_HUMAN MMP8_HUMAN] Can degrade fibrillar type I, II, and III collagens.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Matrix metalloproteinase|Matrix metalloproteinase]]
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*[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Neutrophil collagenase]]
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[[Category: Large Structures]]
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[[Category: Bertini, I]]
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[[Category: Bertini I]]
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[[Category: Calderone, V]]
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[[Category: Calderone V]]
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[[Category: Fragai, M]]
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[[Category: Fragai M]]
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[[Category: Luchinat, C]]
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[[Category: Luchinat C]]
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[[Category: Maletta, M]]
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[[Category: Maletta M]]
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[[Category: Yeo, K J]]
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[[Category: Yeo KJ]]
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[[Category: Hydrolase]]
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[[Category: Matrix metalloproteinase]]
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[[Category: Mmp-8]]
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Current revision

Uninhibited human MMP-8

PDB ID 2oy4

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