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2p02

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[[Image:2p02.gif|left|200px]]
 
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==Crystal structure of the alpha subunit of human S-adenosylmethionine synthetase 2==
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The line below this paragraph, containing "STRUCTURE_2p02", creates the "Structure Box" on the page.
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<StructureSection load='2p02' size='340' side='right'caption='[[2p02]], [[Resolution|resolution]] 1.21&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2p02]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2hj2 2hj2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P02 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P02 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.21&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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{{STRUCTURE_2p02| PDB=2p02 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p02 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p02 OCA], [https://pdbe.org/2p02 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p02 RCSB], [https://www.ebi.ac.uk/pdbsum/2p02 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p02 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/METK2_HUMAN METK2_HUMAN] Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p0/2p02_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p02 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of the alpha subunit of human S-adenosylmethionine synthetase 2'''
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==See Also==
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*[[Methionine adenosyltransferase|Methionine adenosyltransferase]]
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*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]]
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==About this Structure==
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__TOC__
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2P02 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2hj2 2hj2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P02 OCA].
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Methionine adenosyltransferase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Arrowsmith CH]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Edwards A]]
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[[Category: Delft, F von.]]
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[[Category: Gorrec F]]
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[[Category: Edwards, A.]]
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[[Category: Kavanagh KL]]
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[[Category: Gorrec, F.]]
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[[Category: Niessen FH]]
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[[Category: Kavanagh, K L.]]
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[[Category: Oppermann U]]
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[[Category: Niessen, F H.]]
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[[Category: Papagrigoriou E]]
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[[Category: Oppermann, U.]]
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[[Category: Rojkova A]]
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[[Category: Papagrigoriou, E.]]
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[[Category: Shafqat N]]
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[[Category: Rojkova, A.]]
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[[Category: Sundstrom M]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Ugochukwu E]]
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[[Category: Shafqat, N.]]
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[[Category: Weigelt J]]
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[[Category: Sundstrom, M.]]
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[[Category: Von Delft F]]
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[[Category: Ugochukwu, E.]]
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[[Category: Weigelt, J.]]
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[[Category: Sgc]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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[[Category: Synthetase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 12:02:12 2008''
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Current revision

Crystal structure of the alpha subunit of human S-adenosylmethionine synthetase 2

PDB ID 2p02

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