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2q9g
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2q9g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q9G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q9G FirstGlance]. <br> | <table><tr><td colspan='2'>[[2q9g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q9G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q9G FirstGlance]. <br> | ||
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | |
| - | <tr id=' | + | |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q9g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q9g OCA], [https://pdbe.org/2q9g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q9g RCSB], [https://www.ebi.ac.uk/pdbsum/2q9g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q9g ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q9g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q9g OCA], [https://pdbe.org/2q9g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q9g RCSB], [https://www.ebi.ac.uk/pdbsum/2q9g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q9g ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/CP46A_HUMAN CP46A_HUMAN] Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Cholesterol 24-hydroxylase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Johnson | + | [[Category: Johnson EF]] |
| - | [[Category: Mast | + | [[Category: Mast NV]] |
| - | [[Category: Pikuleva | + | [[Category: Pikuleva IA]] |
| - | [[Category: Stout | + | [[Category: Stout CD]] |
| - | [[Category: White | + | [[Category: White MA]] |
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Current revision
Crystal structure of human cytochrome P450 46A1
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