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2qbv

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==Crystal Structure of Intracellular Chorismate Mutase from Mycobacterium Tuberculosis==
==Crystal Structure of Intracellular Chorismate Mutase from Mycobacterium Tuberculosis==
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<StructureSection load='2qbv' size='340' side='right' caption='[[2qbv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2qbv' size='340' side='right'caption='[[2qbv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qbv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QBV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QBV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qbv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QBV FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv0948c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qbv OCA], [https://pdbe.org/2qbv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qbv RCSB], [https://www.ebi.ac.uk/pdbsum/2qbv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qbv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qbv OCA], [http://pdbe.org/2qbv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qbv RCSB], [http://www.ebi.ac.uk/pdbsum/2qbv PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CHMU_MYCTU CHMU_MYCTU] Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.<ref>PMID:15737998</ref> <ref>PMID:18727669</ref> <ref>PMID:19556970</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qb/2qbv_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qb/2qbv_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2qbv" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2qbv" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[3D structures of chorismate mutase|3D structures of chorismate mutase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chorismate mutase]]
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[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Kim, S K]]
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[[Category: Kim SK]]
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[[Category: Ladner, J E]]
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[[Category: Ladner JE]]
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[[Category: Nelson, B C]]
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[[Category: Nelson BC]]
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[[Category: Reddy, P T]]
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[[Category: Reddy PT]]
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[[Category: Reddy, S K]]
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[[Category: Reddy S-K]]
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[[Category: Dimeric]]
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[[Category: Helical]]
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[[Category: Intracellular]]
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[[Category: Isomerase]]
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[[Category: Tuberculosis]]
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Current revision

Crystal Structure of Intracellular Chorismate Mutase from Mycobacterium Tuberculosis

PDB ID 2qbv

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