2qg1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:31, 30 August 2023) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2qg1.gif|left|200px]]
 
-
<!--
+
==Crystal structure of the 11th PDZ domain of MPDZ (MUPP1)==
-
The line below this paragraph, containing "STRUCTURE_2qg1", creates the "Structure Box" on the page.
+
<StructureSection load='2qg1' size='340' side='right'caption='[[2qg1]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2qg1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QG1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QG1 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-
{{STRUCTURE_2qg1| PDB=2qg1 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qg1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qg1 OCA], [https://pdbe.org/2qg1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qg1 RCSB], [https://www.ebi.ac.uk/pdbsum/2qg1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qg1 ProSAT]</span></td></tr>
-
 
+
</table>
-
'''Crystal structure of the 11th PDZ domain of MPDZ (MUPP1)'''
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/MPDZ_HUMAN MPDZ_HUMAN] Interacts with HTR2C and provokes its clustering at the cell surface (By similarity). Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.<ref>PMID:11150294</ref> <ref>PMID:15312654</ref>
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
2QG1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QG1 OCA].
+
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qg/2qg1_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qg1 ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Boisguerin, P.]]
+
[[Category: Boisguerin P]]
-
[[Category: Bunkoczi, G.]]
+
[[Category: Bunkoczi G]]
-
[[Category: Delft, F von.]]
+
[[Category: Doyle D]]
-
[[Category: Doyle, D.]]
+
[[Category: Edwards A]]
-
[[Category: Edwards, A.]]
+
[[Category: Elkins JM]]
-
[[Category: Elkins, J M.]]
+
[[Category: Gileadi C]]
-
[[Category: Gileadi, C.]]
+
[[Category: Oschkinat H]]
-
[[Category: Oschkinat, H.]]
+
[[Category: Papagrigoriou E]]
-
[[Category: Papagrigoriou, E.]]
+
[[Category: Phillips C]]
-
[[Category: Phillips, C.]]
+
[[Category: Salah E]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Savitsky P]]
-
[[Category: Salah, E.]]
+
[[Category: Sundstrom M]]
-
[[Category: Savitsky, P.]]
+
[[Category: Ugochukwu E]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Uppenberg J]]
-
[[Category: Ugochukwu, E.]]
+
[[Category: Weigelt J]]
-
[[Category: Uppenberg, J.]]
+
[[Category: Yang X]]
-
[[Category: Weigelt, J.]]
+
[[Category: Von Delft F]]
-
[[Category: Yang, X.]]
+
-
[[Category: Mpdz]]
+
-
[[Category: Mupp1]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 14:53:15 2008''
+

Current revision

Crystal structure of the 11th PDZ domain of MPDZ (MUPP1)

PDB ID 2qg1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2qg1"
Personal tools