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2qk7

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Current revision (11:34, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2qk7' size='340' side='right'caption='[[2qk7]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='2qk7' size='340' side='right'caption='[[2qk7]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qk7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staaw Staaw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QK7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qk7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MW2 Staphylococcus aureus subsp. aureus MW2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QK7 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1lkf|1lkf]], [[2lkf|2lkf]], [[3lkf|3lkf]], [[1pvl|1pvl]], [[1t5r|1t5r]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hlgA, hlg2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196620 STAAW]), hlgB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196620 STAAW])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qk7 OCA], [https://pdbe.org/2qk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qk7 RCSB], [https://www.ebi.ac.uk/pdbsum/2qk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qk7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qk7 OCA], [https://pdbe.org/2qk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qk7 RCSB], [https://www.ebi.ac.uk/pdbsum/2qk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qk7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/HLGA_STAAU HLGA_STAAU]] Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. [[https://www.uniprot.org/uniprot/HLGB_STAAU HLGB_STAAU]] Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity.
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[https://www.uniprot.org/uniprot/HLGA_STAAU HLGA_STAAU] Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Staaw]]
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[[Category: Staphylococcus aureus subsp. aureus MW2]]
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[[Category: Guillet, V]]
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[[Category: Guillet V]]
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[[Category: Maveyraud, L]]
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[[Category: Maveyraud L]]
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[[Category: Mourey, L]]
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[[Category: Mourey L]]
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[[Category: Roblin, P]]
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[[Category: Roblin P]]
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[[Category: Beta-barrel]]
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[[Category: Covalent complex]]
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[[Category: Cytolysis]]
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[[Category: Hemolysis]]
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[[Category: Molecular plasticity]]
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[[Category: Pore-forming toxin]]
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[[Category: Protein-protein interaction]]
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[[Category: Secreted]]
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[[Category: Toxin]]
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Current revision

A covalent S-F heterodimer of staphylococcal gamma-hemolysin

PDB ID 2qk7

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OCA

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