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2qkr

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==Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound==
==Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound==
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<StructureSection load='2qkr' size='340' side='right' caption='[[2qkr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='2qkr' size='340' side='right'caption='[[2qkr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Crypi Crypi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QKR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qkr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QKR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IXM:(Z)-1H,1H-[2,3]BIINDOLYLIDENE-3,2-DIONE-3-OXIME'>IXM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cgd5_2510 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 CRYPI])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IXM:(Z)-1H,1H-[2,3]BIINDOLYLIDENE-3,2-DIONE-3-OXIME'>IXM</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qkr OCA], [https://pdbe.org/2qkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qkr RCSB], [https://www.ebi.ac.uk/pdbsum/2qkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qkr ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qkr OCA], [http://pdbe.org/2qkr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qkr RCSB], [http://www.ebi.ac.uk/pdbsum/2qkr PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5CRJ8_CRYPI Q5CRJ8_CRYPI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/2qkr_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/2qkr_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qkr ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Crypi]]
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[[Category: Cryptosporidium parvum Iowa II]]
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[[Category: Cyclin-dependent kinase]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Artz, J D]]
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[[Category: Artz JD]]
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[[Category: Bochkarev, A]]
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[[Category: Bochkarev A]]
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[[Category: Dong, A]]
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[[Category: Dong A]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Hassanali, A]]
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[[Category: Hassanali A]]
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[[Category: Hui, R]]
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[[Category: Hui R]]
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[[Category: Lew, J]]
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[[Category: Lew J]]
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[[Category: Lin, Y H]]
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[[Category: Lin YH]]
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[[Category: Structural genomic]]
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[[Category: Sundstrom M]]
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[[Category: Sundstrom, M]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Wernimont AK]]
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[[Category: Wernimont, A K]]
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[[Category: Cp-specific cyclin-dependent kinase]]
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[[Category: Cryptosporidium parvum]]
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[[Category: Malaria]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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Current revision

Cryptosporidium parvum cyclin-dependent kinase cgd5_2510 with indirubin 3'-monoxime bound

PDB ID 2qkr

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