This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2qpf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:37, 30 August 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal Structure of Mouse Transthyretin==
==Crystal Structure of Mouse Transthyretin==
-
<StructureSection load='2qpf' size='340' side='right' caption='[[2qpf]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
+
<StructureSection load='2qpf' size='340' side='right'caption='[[2qpf]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2qpf]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QPF FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2qpf]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QPF FirstGlance]. <br>
-
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ttr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qpf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qpf RCSB], [http://www.ebi.ac.uk/pdbsum/2qpf PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qpf OCA], [https://pdbe.org/2qpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qpf RCSB], [https://www.ebi.ac.uk/pdbsum/2qpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qpf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TTHY_MOUSE TTHY_MOUSE]] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
+
[https://www.uniprot.org/uniprot/TTHY_MOUSE TTHY_MOUSE] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qp/2qpf_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qp/2qpf_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qpf ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 27: Line 28:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2qpf" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Transthyretin|Transthyretin]]
+
*[[Transthyretin 3D structures|Transthyretin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Buxbaum, J N]]
+
[[Category: Buxbaum JN]]
-
[[Category: Foss, T R]]
+
[[Category: Foss TR]]
-
[[Category: Kelly, J W]]
+
[[Category: Kelly JW]]
-
[[Category: Pascual, J]]
+
[[Category: Pascual J]]
-
[[Category: Reixach, N]]
+
[[Category: Reixach N]]
-
[[Category: Santelli, E]]
+
[[Category: Santelli E]]
-
[[Category: Amyloidogenesis]]
+
-
[[Category: Glycoprotein]]
+
-
[[Category: Hormone]]
+
-
[[Category: Retinol-binding]]
+
-
[[Category: Secreted]]
+
-
[[Category: Tetramer]]
+
-
[[Category: Thyroid hormone]]
+
-
[[Category: Transport protein]]
+
-
[[Category: Vitamin some]]
+

Current revision

Crystal Structure of Mouse Transthyretin

PDB ID 2qpf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2qpf"
Personal tools