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2r1w

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==Crystal structure of S25-2 Fab in complex with Kdo analogues==
==Crystal structure of S25-2 Fab in complex with Kdo analogues==
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<StructureSection load='2r1w' size='340' side='right' caption='[[2r1w]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='2r1w' size='340' side='right'caption='[[2r1w]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2r1w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R1W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R1W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2r1w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R1W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R1W FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDB:3,4,5-TRIDEOXY-ALPHA-D-ERYTHRO-OCT-3-EN-2-ULOPYRANOSONIC+ACID'>KDB</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q9q|1q9q]], [[2r1x|2r1x]], [[2r1y|2r1y]], [[2r23|2r23]], [[2r2b|2r2b]], [[2r2e|2r2e]], [[2r2h|2r2h]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDB:3,4,5-TRIDEOXY-ALPHA-D-ERYTHRO-OCT-3-EN-2-ULOPYRANOSONIC+ACID'>KDB</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r1w OCA], [http://pdbe.org/2r1w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2r1w RCSB], [http://www.ebi.ac.uk/pdbsum/2r1w PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r1w OCA], [https://pdbe.org/2r1w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r1w RCSB], [https://www.ebi.ac.uk/pdbsum/2r1w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r1w ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q52L64_MOUSE Q52L64_MOUSE]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/2r1w_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/2r1w_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Monoclonal Antibody|Monoclonal Antibody]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Brooks, C L]]
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[[Category: Brooks CL]]
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[[Category: Evans, S V]]
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[[Category: Evans SV]]
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[[Category: Anti-carbohydrate antibody]]
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[[Category: Fab]]
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[[Category: Immune system]]
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[[Category: Immunoglobulin c region]]
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[[Category: Immunoglobulin domain]]
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[[Category: Immunoglobulin v region]]
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[[Category: Secreted]]
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Current revision

Crystal structure of S25-2 Fab in complex with Kdo analogues

PDB ID 2r1w

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