This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.

3bgv

From Proteopedia

(Difference between revisions)

Jump to: navigation, search

Current revision

Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with SAH

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3bgv"

@@ Line 1: / Line 1: @@
 ==Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with SAH==
-<StructureSection load='3bgv' size='340' side='right' caption='[[3bgv]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+<StructureSection load='3bgv' size='340' side='right'caption='[[3bgv]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3bgv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BGV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BGV FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3bgv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BGV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BGV FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNMT, KIAA0398 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/mRNA_(guanine-N(7)-)-methyltransferase mRNA (guanine-N(7)-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.56 2.1.1.56] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bgv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bgv OCA], [https://pdbe.org/3bgv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bgv RCSB], [https://www.ebi.ac.uk/pdbsum/3bgv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bgv ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bgv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bgv OCA], [http://pdbe.org/3bgv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bgv RCSB], [http://www.ebi.ac.uk/pdbsum/3bgv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bgv ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/MCES_HUMAN MCES_HUMAN]] mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.<ref>PMID:9790902</ref> <ref>PMID:9705270</ref> <ref>PMID:10347220</ref> <ref>PMID:22099306</ref>
+[https://www.uniprot.org/uniprot/MCES_HUMAN MCES_HUMAN] mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.<ref>PMID:9790902</ref> <ref>PMID:9705270</ref> <ref>PMID:10347220</ref> <ref>PMID:22099306</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 25: / Line 24: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Antoshenko, T]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C H]]
+[[Category: Antoshenko T]]
-[[Category: Bochkarev, A]]
+[[Category: Arrowsmith CH]]
-[[Category: Edwards, A M]]
+[[Category: Bochkarev A]]
-[[Category: Lunin, V V]]
+[[Category: Edwards AM]]
-[[Category: MacKenzie, F]]
+[[Category: Lunin VV]]
-[[Category: Min, J]]
+[[Category: MacKenzie F]]
-[[Category: Plotnikov, A N]]
+[[Category: Min J]]
-[[Category: Structural genomic]]
+[[Category: Plotnikov AN]]
-[[Category: Weigelt, J]]
+[[Category: Weigelt J]]
-[[Category: Wu, H]]
+[[Category: Wu H]]
-[[Category: Zeng, H]]
+[[Category: Zeng H]]
-[[Category: Alternative splicing]]
-[[Category: Methyltransferase]]
-[[Category: Mrna capping]]
-[[Category: Mrna processing]]
-[[Category: Nucleus]]
-[[Category: Phosphoprotein]]
-[[Category: Rna-binding]]
-[[Category: S-adenosyl-l-methionine]]
-[[Category: Sgc]]
-[[Category: Transferase]]

3bgv

From Proteopedia

Current revision

Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with SAH

Structural highlights

Function

Evolutionary Conservation

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox