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3ciu

From Proteopedia

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[[Image:3ciu.png|left|200px]]
 
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{{STRUCTURE_3ciu| PDB=3ciu | SCENE= }}
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==Site-Selective Glycosylation of Cysteine-93 beta on the Surface of Bovine Hemoglobin and its Application as a Novel Oxygen Therapeutic==
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<StructureSection load='3ciu' size='340' side='right'caption='[[3ciu]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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===Site-Selective Glycosylation of Cysteine-93 beta on the Surface of Bovine Hemoglobin and its Application as a Novel Oxygen Therapeutic===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ciu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CIU FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5DP:5-(2,5-DIOXOPYRROLIDIN-1-YL)-N-[2-(2-{2-[(4-O-ALPHA-D-IDOPYRANOSYL-ALPHA-D-MANNOPYRANOSYL)OXY]ETHOXY}ETHOXY)ETHYL]PENTANAMIDE'>5DP</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene></td></tr>
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[[3ciu]] is a 4 chain structure of [[Hemoglobin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CIU OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ciu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ciu OCA], [https://pdbe.org/3ciu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ciu RCSB], [https://www.ebi.ac.uk/pdbsum/3ciu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ciu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HBA_BOVIN HBA_BOVIN] Involved in oxygen transport from the lung to the various peripheral tissues.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ci/3ciu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ciu ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Hemoglobin|Hemoglobin]]
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*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
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__TOC__
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Bhatt, V S.]]
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[[Category: Large Structures]]
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[[Category: Palmer, A F.]]
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[[Category: Bhatt VS]]
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[[Category: Sun, G.]]
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[[Category: Palmer AF]]
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[[Category: Wang, P G.]]
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[[Category: Sun G]]
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[[Category: Zhang, Y.]]
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[[Category: Wang PG]]
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[[Category: Blood substitute]]
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[[Category: Zhang Y]]
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[[Category: Glycosylation]]
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[[Category: Heme]]
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[[Category: Hemoglobin]]
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[[Category: Iron]]
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[[Category: Oxygen binding]]
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[[Category: Oxygen carrier]]
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[[Category: Oxygen transport]]
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[[Category: Site-selective]]
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[[Category: Transport]]
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Current revision

Site-Selective Glycosylation of Cysteine-93 beta on the Surface of Bovine Hemoglobin and its Application as a Novel Oxygen Therapeutic

PDB ID 3ciu

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