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3ckk

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Crystal structure of human methyltransferase-like protein 1

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Retrieved from "http://52.214.119.220/wiki/index.php/3ckk"

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-[[Image:3ckk.jpg|left|200px]]
- {{Structure
+==Crystal structure of human methyltransferase-like protein 1==
-|PDB= 3ckk |SIZE=350|CAPTION= <scene name='initialview01'>3ckk</scene>, resolution 1.55&Aring;
+<StructureSection load='3ckk' size='340' side='right'caption='[[3ckk]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
-|SITE= <scene name='pdbsite=AC1:Sam+Binding+Site+For+Residue+A+301'>AC1</scene> and <scene name='pdbsite=AC2:Gol+Binding+Site+For+Residue+A+302'>AC2</scene>
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>
+<table><tr><td colspan='2'>[[3ckk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CKK FirstGlance]. <br>
-|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine-N(7)-)-methyltransferase tRNA (guanine-N(7)-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.33 2.1.1.33] </span>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
-|GENE= METTL1, C12orf1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam02390 Methyltransf_4]</span>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ckk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ckk OCA], [https://pdbe.org/3ckk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ckk RCSB], [https://www.ebi.ac.uk/pdbsum/3ckk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ckk ProSAT]</span></td></tr>
-|RELATEDENTRY=
+</table>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ckk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ckk OCA], [http://www.ebi.ac.uk/pdbsum/3ckk PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3ckk RCSB]</span>
+== Function ==
-}}
+[https://www.uniprot.org/uniprot/TRMB_HUMAN TRMB_HUMAN] Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<ref>PMID:12403464</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/3ckk_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ckk ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of human methyltransferase-like protein 1'''
+==See Also==
+*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-CKK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKK OCA].
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: tRNA (guanine-N(7)-)-methyltransferase]]
+[[Category: Arrowsmith CH]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Bochkarev A]]
-[[Category: Bochkarev, A.]]
+[[Category: Bountra C]]
-[[Category: Bountra, C.]]
+[[Category: Dobrovetsky E]]
-[[Category: Dobrovetsky, E.]]
+[[Category: Dong A]]
-[[Category: Dong, A.]]
+[[Category: Edwards AM]]
-[[Category: Edwards, A M.]]
+[[Category: Min J]]
-[[Category: Min, J.]]
+[[Category: Plotnikov AN]]
-[[Category: Plotnikov, A N.]]
+[[Category: Weigelt J]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Wu H]]
-[[Category: Weigelt, J.]]
+[[Category: Zeng H]]
-[[Category: Wu, H.]]
-[[Category: Zeng, H.]]
-[[Category: methyltransferase]]
-[[Category: mettl1]]
-[[Category: s-adenosyl-l-methionine]]
-[[Category: sgc]]
-[[Category: structural genomic]]
-[[Category: structural genomics consortium]]
-[[Category: trna processing]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr  2 12:00:23 2008''

3ckk

From Proteopedia

Current revision

Crystal structure of human methyltransferase-like protein 1

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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