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3cw8

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==4-Chlorobenzoyl-CoA Ligase/Synthetase, bound to 4CBA-Adenylate==
==4-Chlorobenzoyl-CoA Ligase/Synthetase, bound to 4CBA-Adenylate==
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<StructureSection load='3cw8' size='340' side='right' caption='[[3cw8]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='3cw8' size='340' side='right'caption='[[3cw8]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3cw8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Alcaligenes_sp. Alcaligenes sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CW8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CW8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3cw8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcaligenes_sp._AL3007 Alcaligenes sp. AL3007]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CW8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=00A:5-O-[(S)-{[(4-CHLOROPHENYL)CARBONYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE'>00A</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1t5d|1t5d]], [[1pg4|1pg4]], [[3cw9|3cw9]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=00A:5-O-[(S)-{[(4-CHLOROPHENYL)CARBONYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE'>00A</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-chlorobenzoate--CoA_ligase 4-chlorobenzoate--CoA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.2.1.33 6.2.1.33] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cw8 OCA], [https://pdbe.org/3cw8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cw8 RCSB], [https://www.ebi.ac.uk/pdbsum/3cw8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cw8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cw8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cw8 RCSB], [http://www.ebi.ac.uk/pdbsum/3cw8 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8GN86_9BURK Q8GN86_9BURK]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cw/3cw8_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cw/3cw8_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cw8 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3cw8" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 4-chlorobenzoate--CoA ligase]]
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[[Category: Alcaligenes sp. AL3007]]
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[[Category: Alcaligenes sp.]]
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[[Category: Large Structures]]
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[[Category: Cao, J.]]
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[[Category: Cao J]]
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[[Category: Dunaway-Mariano, D.]]
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[[Category: Dunaway-Mariano D]]
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[[Category: Gulick, A M.]]
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[[Category: Gulick AM]]
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[[Category: Reger, A S.]]
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[[Category: Reger AS]]
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[[Category: Wu, R.]]
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[[Category: Wu R]]
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[[Category: Acyl-coa ligase]]
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[[Category: Adenylate-forming enzyme]]
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[[Category: Ligase]]
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Current revision

4-Chlorobenzoyl-CoA Ligase/Synthetase, bound to 4CBA-Adenylate

PDB ID 3cw8

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