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3d9m

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==Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II==
==Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II==
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<StructureSection load='3d9m' size='340' side='right' caption='[[3d9m]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='3d9m' size='340' side='right'caption='[[3d9m]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3d9m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D9M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3d9m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D9M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sz9|1sz9]], [[1sza|1sza]], [[2bf0|2bf0]], [[3clj|3clj]], [[3d9i|3d9i]], [[3d9j|3d9j]], [[3d9k|3d9k]], [[3d9l|3d9l]], [[3d9n|3d9n]], [[3d9o|3d9o]], [[3d9p|3d9p]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d9m OCA], [https://pdbe.org/3d9m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d9m RCSB], [https://www.ebi.ac.uk/pdbsum/3d9m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d9m ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBM16, KIAA1116 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d9m OCA], [http://pdbe.org/3d9m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3d9m RCSB], [http://www.ebi.ac.uk/pdbsum/3d9m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3d9m ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SCAF8_HUMAN SCAF8_HUMAN]] May play a role in mRNA processing.<ref>PMID:11101529</ref>
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[https://www.uniprot.org/uniprot/SCAF8_HUMAN SCAF8_HUMAN] May play a role in mRNA processing.<ref>PMID:11101529</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d9/3d9m_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d9/3d9m_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Becker, R]]
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[[Category: Large Structures]]
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[[Category: Loll, B]]
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[[Category: Becker R]]
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[[Category: Meinhart, A]]
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[[Category: Loll B]]
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[[Category: Arm repeat]]
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[[Category: Meinhart A]]
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[[Category: Phospho-ctd]]
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[[Category: Phosphoprotein]]
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[[Category: Rna polymerase ii ctd interacting domain]]
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[[Category: Rna-binding]]
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[[Category: Scaf8]]
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[[Category: Transcription]]
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Current revision

Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II

PDB ID 3d9m

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