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3dbc
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==Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 257== | ==Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 257== | ||
| - | <StructureSection load='3dbc' size='340' side='right' caption='[[3dbc]], [[Resolution|resolution]] 3.35Å' scene=''> | + | <StructureSection load='3dbc' size='340' side='right'caption='[[3dbc]], [[Resolution|resolution]] 3.35Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3dbc]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3dbc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DBC FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.35Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2FR:3-[3-(3-METHYL-6-{[(1S)-1-PHENYLETHYL]AMINO}-1H-PYRAZOLO[4,3-C]PYRIDIN-1-YL)PHENYL]PROPANAMIDE'>2FR</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dbc OCA], [https://pdbe.org/3dbc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dbc RCSB], [https://www.ebi.ac.uk/pdbsum/3dbc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dbc ProSAT]</span></td></tr> |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q4KMI8_DANRE Q4KMI8_DANRE] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | + | *[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Danio rerio]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Barr | + | [[Category: Barr KJ]] |
| - | [[Category: Elling | + | [[Category: Elling RA]] |
| - | [[Category: Romanowski | + | [[Category: Romanowski MJ]] |
| - | [[Category: Zhu | + | [[Category: Zhu J]] |
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Current revision
Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 257
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