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3dr6
From Proteopedia
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==Structure of yncA, a putative ACETYLTRANSFERASE from Salmonella typhimurium== | ==Structure of yncA, a putative ACETYLTRANSFERASE from Salmonella typhimurium== | ||
| - | <StructureSection load='3dr6' size='340' side='right' caption='[[3dr6]], [[Resolution|resolution]] 1.75Å' scene=''> | + | <StructureSection load='3dr6' size='340' side='right'caption='[[3dr6]], [[Resolution|resolution]] 1.75Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3dr6]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3dr6]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DR6 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dr6 OCA], [https://pdbe.org/3dr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dr6 RCSB], [https://www.ebi.ac.uk/pdbsum/3dr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dr6 ProSAT], [https://www.topsan.org/Proteins/CSGID/3dr6 TOPSAN]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MDDA_SALTY MDDA_SALTY] Plays a role in the resistance against the toxic effects of L-methionine sulfoximine (MSX), a rare amino acid which inhibits glutamine synthetase (GlnA). Catalyzes the acetylation of MSX. It can also use L-methionine sulfone (MSO) (PubMed:25368301). Also catalyzes the acylation of free L-amino acids using an acyl-CoA as acyl donor (By similarity).[UniProtKB:P76112]<ref>PMID:25368301</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dr/3dr6_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dr/3dr6_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dr6 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Salmonella enterica subsp. enterica serovar | + | [[Category: Large Structures]] |
| - | [[Category: Anderson | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]] |
| - | + | [[Category: Anderson WF]] | |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Onopriyenko | + | [[Category: Onopriyenko O]] |
| - | [[Category: Savchenko | + | [[Category: Savchenko A]] |
| - | [[Category: Singer | + | [[Category: Singer AU]] |
| - | [[Category: Skarina | + | [[Category: Skarina T]] |
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Current revision
Structure of yncA, a putative ACETYLTRANSFERASE from Salmonella typhimurium
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