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7z4t
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7z4t is ON HOLD Authors: Rondeau, J.M., Lehmann, S. Description: AAL160 FAB IN COMPLEX WITH HUMAN INTERLEUKIN-1 BETA [[Category: Unreleased Structu...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==AAL160 FAB IN COMPLEX WITH HUMAN INTERLEUKIN-1 BETA== | |
| - | + | <StructureSection load='7z4t' size='340' side='right'caption='[[7z4t]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7z4t]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z4T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z4t OCA], [https://pdbe.org/7z4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z4t RCSB], [https://www.ebi.ac.uk/pdbsum/7z4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z4t ProSAT]</span></td></tr> |
| - | [[Category: Lehmann | + | </table> |
| - | [[Category: Rondeau | + | == Function == |
| + | [https://www.uniprot.org/uniprot/IL1B_HUMAN IL1B_HUMAN] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.<ref>PMID:3920526</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lehmann S]] | ||
| + | [[Category: Rondeau JM]] | ||
Current revision
AAL160 FAB IN COMPLEX WITH HUMAN INTERLEUKIN-1 BETA
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