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2bc7
From Proteopedia
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==Solution structure of [Sec2,8]-ImI== | ==Solution structure of [Sec2,8]-ImI== | ||
| - | <StructureSection load='2bc7' size='340' side='right'caption='[[2bc7 | + | <StructureSection load='2bc7' size='340' side='right'caption='[[2bc7]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2bc7]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BC7 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[2bc7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_imperialis Conus imperialis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BC7 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bc7 OCA], [https://pdbe.org/2bc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bc7 RCSB], [https://www.ebi.ac.uk/pdbsum/2bc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bc7 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bc7 OCA], [https://pdbe.org/2bc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bc7 RCSB], [https://www.ebi.ac.uk/pdbsum/2bc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bc7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/CA1_CONIM CA1_CONIM] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks mammalian neuronal nAChRs (alpha-3/beta-2 > alpha-7 > alpha-3/beta-4). Has no effect on nAChRs composed of alpha-2/beta-2, alpha-3/beta-2, alpha-4/beta-2, alpha-2/beta-4, alpha-3/beta-4, or alpha-4/beta-4 subunits. Acts voltage-independently. Is highly active against the neuromuscular receptor in frog.<ref>PMID:8206995</ref> | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Conus imperialis]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Armishaw | + | [[Category: Armishaw CJ]] |
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Current revision
Solution structure of [Sec2,8]-ImI
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