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2ypd
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2ypd is ON HOLD Authors: Vollmar, M., Johansson, C., Krojer, T., Strain-Damerell, C., Froese, S., Williams, E., Coutandin, D., von Delft, F., Weigel...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the Jumonji domain of human Jumonji domain containing 1C protein== | |
| - | + | <StructureSection load='2ypd' size='340' side='right'caption='[[2ypd]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2ypd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YPD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EMT:2-(ETHYLMERCURI-THIO)-BENZOIC+ACID'>EMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ypd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ypd OCA], [https://pdbe.org/2ypd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ypd RCSB], [https://www.ebi.ac.uk/pdbsum/2ypd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ypd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/JHD2C_HUMAN JHD2C_HUMAN] Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Berridge G]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Burgess-Brown N]] | ||
| + | [[Category: Coutandin D]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Froese S]] | ||
| + | [[Category: Goubin S]] | ||
| + | [[Category: Johansson C]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: Oppermann U]] | ||
| + | [[Category: Strain-Damerell C]] | ||
| + | [[Category: Vollmar M]] | ||
| + | [[Category: Williams E]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of the Jumonji domain of human Jumonji domain containing 1C protein
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Berridge G | Bountra C | Burgess-Brown N | Coutandin D | Edwards A | Froese S | Goubin S | Johansson C | Krojer T | Oppermann U | Strain-Damerell C | Vollmar M | Williams E | Von Delft F
