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5icj

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Current revision (13:45, 30 August 2023) (edit) (undo)
 
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==Crystal structure of the Mycobacterium tuberculosis transcriptional repressor EthR2 in complex with BDM41420==
==Crystal structure of the Mycobacterium tuberculosis transcriptional repressor EthR2 in complex with BDM41420==
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<StructureSection load='5icj' size='340' side='right' caption='[[5icj]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='5icj' size='340' side='right'caption='[[5icj]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5icj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ICJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ICJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5icj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ICJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ICJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=69Y:4,4,4-TRIFLUORO-1-(3-PHENYL-1-OXA-2,8-DIAZASPIRO[4.5]DEC-2-EN-8-YL)BUTAN-1-ONE'>69Y</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv0078, LH57_00450 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=69Y:4,4,4-TRIFLUORO-1-(3-PHENYL-1-OXA-2,8-DIAZASPIRO[4.5]DEC-2-EN-8-YL)BUTAN-1-ONE'>69Y</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5icj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5icj OCA], [http://pdbe.org/5icj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5icj RCSB], [http://www.ebi.ac.uk/pdbsum/5icj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5icj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5icj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5icj OCA], [https://pdbe.org/5icj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5icj RCSB], [https://www.ebi.ac.uk/pdbsum/5icj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5icj ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O53623_MYCTU O53623_MYCTU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baulard, A R]]
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[[Category: Large Structures]]
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[[Category: Meyer, F]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Remaut, H]]
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[[Category: Baulard AR]]
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[[Category: Tanina, A]]
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[[Category: Meyer F]]
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[[Category: Willand, N]]
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[[Category: Remaut H]]
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[[Category: Wintjens, R]]
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[[Category: Tanina A]]
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[[Category: Wohlkonig, A]]
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[[Category: Willand N]]
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[[Category: Helix-turn-helix dna binding protein]]
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[[Category: Wintjens R]]
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[[Category: Inhibitor]]
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[[Category: Wohlkonig A]]
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[[Category: Regulatory repressor]]
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[[Category: Tetr family]]
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[[Category: Transcription]]
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[[Category: Transcription repressor-inhibitor complex]]
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Current revision

Crystal structure of the Mycobacterium tuberculosis transcriptional repressor EthR2 in complex with BDM41420

PDB ID 5icj

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