This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5ikw
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5ikw is ON HOLD Authors: Counago, R.M., Sorrell, F.J., Krojer, T., Savitsky, P., Elkins, J.M., Axtman, A., Drewry, D., Wells, C., Zhang, C., Zuerche...) |
|||
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor== | |
| - | + | <StructureSection load='5ikw' size='340' side='right'caption='[[5ikw]], [[Resolution|resolution]] 2.41Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ikw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IKW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IKW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6BU:N-(6-{3-[(CYCLOPROPYLSULFONYL)AMINO]PHENYL}-1H-INDAZOL-3-YL)CYCLOPROPANECARBOXAMIDE'>6BU</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ikw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ikw OCA], [https://pdbe.org/5ikw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ikw RCSB], [https://www.ebi.ac.uk/pdbsum/5ikw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ikw ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/BMP2K_HUMAN BMP2K_HUMAN] May be involved in osteoblast differentiation. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Arruda P]] |
| - | [[Category: | + | [[Category: Axtman A]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Counago RM]] |
| - | [[Category: | + | [[Category: Drewry D]] |
| - | [[Category: | + | [[Category: Edwards AM]] |
| - | [[Category: Zhang | + | [[Category: Elkins JM]] |
| - | [[Category: | + | [[Category: Gileadi O]] |
| + | [[Category: Krojer T]] | ||
| + | [[Category: Savitsky P]] | ||
| + | [[Category: Sorrell FJ]] | ||
| + | [[Category: Wells C]] | ||
| + | [[Category: Willson TM]] | ||
| + | [[Category: Zhang C]] | ||
| + | [[Category: Zuercher W]] | ||
Current revision
Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Arruda P | Axtman A | Bountra C | Counago RM | Drewry D | Edwards AM | Elkins JM | Gileadi O | Krojer T | Savitsky P | Sorrell FJ | Wells C | Willson TM | Zhang C | Zuercher W
