Plexin

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*<scene name='46/466532/Cv/4'>Plexin C1 interactions with semaphoric SEMA7A</scene>. Water molecules are shown as red spheres.
*<scene name='46/466532/Cv/4'>Plexin C1 interactions with semaphoric SEMA7A</scene>. Water molecules are shown as red spheres.
*<scene name='46/466532/Cv/5'>Ca coordination site</scene>.
*<scene name='46/466532/Cv/5'>Ca coordination site</scene>.
 +
==3D structures of plexin==
 +
[[Plexin 3D structures]]
</StructureSection>
</StructureSection>
==3D structures of plexin==
==3D structures of plexin==

Revision as of 08:39, 3 September 2023

Glycosylated human plexin C1 (magenta) complex with semaphoric SEMA7A (green) and Ca+2 ion (green) (PDB entry 3nvn)

Drag the structure with the mouse to rotate

3D structures of plexin

03-September-2023

References

  1. Janssen BJ, Robinson RA, Perez-Branguli F, Bell CH, Mitchell KJ, Siebold C, Jones EY. Structural basis of semaphorin-plexin signalling. Nature. 2010 Sep 26. PMID:20877282 doi:10.1038/nature09468
  2. Winberg ML, Noordermeer JN, Tamagnone L, Comoglio PM, Spriggs MK, Tessier-Lavigne M, Goodman CS. Plexin A is a neuronal semaphorin receptor that controls axon guidance. Cell. 1998 Dec 23;95(7):903-16. PMID:9875845
  3. Perrot V, Vazquez-Prado J, Gutkind JS. Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF. J Biol Chem. 2002 Nov 8;277(45):43115-20. Epub 2002 Aug 14. PMID:12183458 doi:http://dx.doi.org/10.1074/jbc.M206005200
  4. Tamagnone L, Artigiani S, Chen H, He Z, Ming GI, Song H, Chedotal A, Winberg ML, Goodman CS, Poo M, Tessier-Lavigne M, Comoglio PM. Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. Cell. 1999 Oct 1;99(1):71-80. PMID:10520995

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