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3fvc
From Proteopedia
(Difference between revisions)
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<StructureSection load='3fvc' size='340' side='right'caption='[[3fvc]], [[Resolution|resolution]] 3.20Å' scene=''> | <StructureSection load='3fvc' size='340' side='right'caption='[[3fvc]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3fvc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3fvc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_4_strain_B95-8 Human herpesvirus 4 strain B95-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FVC FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvc OCA], [https://pdbe.org/3fvc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fvc RCSB], [https://www.ebi.ac.uk/pdbsum/3fvc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fvc ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvc OCA], [https://pdbe.org/3fvc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fvc RCSB], [https://www.ebi.ac.uk/pdbsum/3fvc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fvc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/GB_EBVB9 GB_EBVB9] Envelope glycoprotein that forms spikes at the surface of virion envelope. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding of gp350/220 to its receptor, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</div> | </div> | ||
<div class="pdbe-citations 3fvc" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3fvc" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Glycoproteins B and D|Glycoproteins B and D]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human herpesvirus 4 strain B95-8]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Backovic | + | [[Category: Backovic M]] |
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Current revision
Crystal structure of a trimeric variant of the Epstein-Barr virus glycoprotein B
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