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3g9k

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==Crystal structure of Bacillus anthracis transpeptidase enzyme CapD==
==Crystal structure of Bacillus anthracis transpeptidase enzyme CapD==
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<StructureSection load='3g9k' size='340' side='right' caption='[[3g9k]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
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<StructureSection load='3g9k' size='340' side='right'caption='[[3g9k]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3g9k]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G9K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G9K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3g9k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G9K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G9K FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ga9|3ga9]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g9k OCA], [https://pdbe.org/3g9k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g9k RCSB], [https://www.ebi.ac.uk/pdbsum/3g9k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g9k ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAK_B0097, BXB0063, capD, dep, GBAA_pXO2_0063, pXO2-55 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946]), capD, dep, pXO2-55, BXB0063, GBAA_pXO2_0063 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 "Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g9k OCA], [http://pdbe.org/3g9k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3g9k RCSB], [http://www.ebi.ac.uk/pdbsum/3g9k PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CAPD_BACAN CAPD_BACAN]] Degradation of the high-molecular weight capsule (H-capsule) to the lower-molecular weight capsule (L-capsule), which is released from the bacterial cell surface. The production of L-capsule is essential to mediate escape from host defenses. Does not have gamma-glutamyltranspeptidase (GGT) activity.<ref>PMID:8105361</ref> <ref>PMID:12134259</ref>
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[https://www.uniprot.org/uniprot/CAPD_BACAN CAPD_BACAN] Degradation of the high-molecular weight capsule (H-capsule) to the lower-molecular weight capsule (L-capsule), which is released from the bacterial cell surface. The production of L-capsule is essential to mediate escape from host defenses. Does not have gamma-glutamyltranspeptidase (GGT) activity.<ref>PMID:8105361</ref> <ref>PMID:12134259</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g9/3g9k_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g9/3g9k_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anderson, V J]]
 
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[[Category: GLRCE, The Great Lakes Regional Center of Excellence]]
 
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[[Category: Joachimiak, A]]
 
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[[Category: Missiakas, D]]
 
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[[Category: Richter, S]]
 
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[[Category: Wu, R]]
 
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[[Category: Zhang, R]]
 
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
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[[Category: Capd protein]]
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[[Category: Large Structures]]
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[[Category: Capsule biogenesis/degradation]]
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[[Category: Anderson VJ]]
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[[Category: Glrce]]
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[[Category: Joachimiak A]]
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[[Category: Hydrolase]]
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[[Category: Missiakas D]]
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[[Category: The great lakes regional center of excellence]]
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[[Category: Richter S]]
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[[Category: Virulence]]
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[[Category: Wu R]]
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[[Category: Zhang R]]

Current revision

Crystal structure of Bacillus anthracis transpeptidase enzyme CapD

PDB ID 3g9k

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