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3ghb

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==Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 peptide W2RW020==
==Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 peptide W2RW020==
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<StructureSection load='3ghb' size='340' side='right' caption='[[3ghb]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='3ghb' size='340' side='right'caption='[[3ghb]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ghb]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GHB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GHB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ghb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GHB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q1j|1q1j]], [[3c2a|3c2a]], [[3ghe|3ghe]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ghb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ghb OCA], [http://pdbe.org/3ghb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ghb RCSB], [http://www.ebi.ac.uk/pdbsum/3ghb PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ghb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ghb OCA], [https://pdbe.org/3ghb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ghb RCSB], [https://www.ebi.ac.uk/pdbsum/3ghb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ghb ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/P88213_9HIV1 P88213_9HIV1]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gh/3ghb_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gh/3ghb_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Antibody|Antibody]]
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[3D structures of human antibody|3D structures of human antibody]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Burke, V J]]
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[[Category: Human immunodeficiency virus 1]]
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[[Category: Kong, X P]]
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[[Category: Large Structures]]
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[[Category: Antibody-antigen interaction]]
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[[Category: Burke VJ]]
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[[Category: Envelope protein]]
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[[Category: Kong XP]]
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[[Category: Hiv]]
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[[Category: Immune system]]
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[[Category: V3 loop]]
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Current revision

Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 peptide W2RW020

PDB ID 3ghb

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