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3h5f

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{{Seed}}
 
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[[Image:3h5f.png|left|200px]]
 
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==Switching the Chirality of the Metal Environment Alters the Coordination Mode in Designed Peptides.==
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The line below this paragraph, containing "STRUCTURE_3h5f", creates the "Structure Box" on the page.
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<StructureSection load='3h5f' size='340' side='right'caption='[[3h5f]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3h5f]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H5F FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LE1:3-SULFANYL-L-VALINE'>LE1</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3h5f| PDB=3h5f | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h5f OCA], [https://pdbe.org/3h5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h5f RCSB], [https://www.ebi.ac.uk/pdbsum/3h5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h5f ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The effects of switching the chirality of a single layer of amino acids in a three stranded coiled coil has been investigated. X-ray crystallography reveals that this modification is well tolerated and does not alter the designed structure. In contrast, spectroscopic studies of cadmium binding to both the L- and D- enantiomers of the penicillamine, provide evidence that this switch dramatically alters the metal binding capability, the resulting coordination environment and the position of binding.
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===Switching the Chirality of the Metal Environment Alters the Coordination Mode in Designed Peptides.===
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Switching the chirality of the metal environment alters the coordination mode in designed peptides.,Peacock AF, Stuckey JA, Pecoraro VL Angew Chem Int Ed Engl. 2009;48(40):7371-4. doi: 10.1002/anie.200902166. PMID:19579245<ref>PMID:19579245</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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3H5F is a 3 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H5F OCA].
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<div class="pdbe-citations 3h5f" style="background-color:#fffaf0;"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:19579245</ref><references group="xtra"/>
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__TOC__
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[[Category: Peacock, A F.A.]]
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</StructureSection>
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[[Category: Pecoraro, V L.]]
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[[Category: Large Structures]]
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[[Category: Stuckey, J A.]]
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[[Category: Peacock AFA]]
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[[Category: De novo protein]]
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[[Category: Pecoraro VL]]
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[[Category: De-novo protein]]
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[[Category: Stuckey JA]]
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[[Category: L-penicillamine]]
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[[Category: Parallel three-stranded coiled coil]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 08:46:55 2009''
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Current revision

Switching the Chirality of the Metal Environment Alters the Coordination Mode in Designed Peptides.

PDB ID 3h5f

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