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3h80

From Proteopedia

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[[Image:3h80.png|left|200px]]
 
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{{STRUCTURE_3h80| PDB=3h80 | SCENE= }}
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==Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LmjF33.0312:M1-K213==
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<StructureSection load='3h80' size='340' side='right'caption='[[3h80]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LmjF33.0312:M1-K213===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3h80]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major_strain_Friedlin Leishmania major strain Friedlin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H80 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H80 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[3h80]] is a 1 chain structure of [[Heat Shock Proteins]] with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H80 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h80 OCA], [https://pdbe.org/3h80 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h80 RCSB], [https://www.ebi.ac.uk/pdbsum/3h80 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h80 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q4Q4I6_LEIMA Q4Q4I6_LEIMA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/3h80_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h80 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Heat Shock Proteins|Heat Shock Proteins]]
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
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[[Category: Leishmania major]]
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__TOC__
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[[Category: Arrowsmith, C H.]]
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</StructureSection>
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[[Category: Bochkarev, A.]]
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[[Category: Large Structures]]
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[[Category: Bountra, C.]]
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[[Category: Leishmania major strain Friedlin]]
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[[Category: Cossar, D.]]
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[[Category: Arrowsmith CH]]
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[[Category: Edwards, A M.]]
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[[Category: Bochkarev A]]
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[[Category: Fairlamb, A.]]
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[[Category: Bountra C]]
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[[Category: Ferguson, M A.J.]]
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[[Category: Cossar D]]
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[[Category: Hills, T.]]
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[[Category: Edwards AM]]
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[[Category: Hui, R.]]
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[[Category: Fairlamb A]]
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[[Category: Hutchinson, A.]]
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[[Category: Ferguson MAJ]]
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[[Category: Kozieradzki, I.]]
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[[Category: Hills T]]
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[[Category: Lin, Y H.]]
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[[Category: Hui R]]
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[[Category: Mackenzie, F.]]
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[[Category: Hutchinson A]]
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[[Category: Pizarro, J C.]]
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[[Category: Kozieradzki I]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Lin YH]]
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[[Category: Schapira, M.]]
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[[Category: Mackenzie F]]
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[[Category: Tempel, W.]]
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[[Category: Pizarro JC]]
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[[Category: Weigelt, J.]]
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[[Category: Schapira M]]
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[[Category: Wernimont, A K.]]
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[[Category: Tempel W]]
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[[Category: Zhao, Y.]]
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[[Category: Weigelt J]]
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[[Category: Chaperone]]
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[[Category: Wernimont AK]]
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[[Category: Heat shock protein]]
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[[Category: Zhao Y]]
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[[Category: Leishmania]]
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[[Category: Sgc]]
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[[Category: Sleeping sickness]]
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[[Category: Stress response protein]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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Current revision

Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LmjF33.0312:M1-K213

PDB ID 3h80

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